Advances in Whole Genome Sequencing for Foodborne Pathogens: Implications for Clinical Infectious Disease Surveillance and Public Health
Foodborne outbreaks pose a growing global health threat, with traditional methods lacking precision and resolution. Whole genome sequencing (WGS) has emerged as a revolutionary tool for outbreak investigations, providing high-resolution genetic data for accurate species identification and strain differentiation. WGS also aids in detecting virulence and antimicrobial resistance genes, enhancing outbreak surveillance and risk assessment. Despite challenges like high sequencing costs, specialized bioinformatics expertise, limited computational infrastructure, and standardization of data-sharing frameworks, WGS is becoming a vital tool in food safety and public health.
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